Diabetes Management Information
Learn more about the basics of diabetes, insulin, and more.


Type 2 Diabetes
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Glossary
Type 2 Diabetes
A condition characterized by high blood glucose levels caused by either a lack of insulin or the body's inability to use insulin efficiently. Type 2 diabetes develops most often in middle-aged and older adults but can appear in young people, and is the most common form of diabetes.
Glossary
Insulin
A hormone produced in the pancreas by beta cells, which is necessary for glucose (blood sugar) to be able to enter certain cells of the body and be used for energy.
Glossary
Insulin Resistance
The body's inability to respond to and use the insulin it produces. Insulin resistance may be linked to obesity, hypertension, and high levels of fat in the blood.
Glossary
Blood Sugar Level
The amount of sugar (glucose) in a given amount of blood. It is reported as the number of milligrams of glucose in a deciliter of blood, or mg/dL.
In type 2 diabetes, your body may still make insulin, but is unable to correctly use the insulin it does make (insulin resistance). Eventually the body doesn't make enough insulin (insulin deficiency). People who have it can be treated with proper meal planning, exercise, and medications. Type 2 diabetes is the most common form of diabetes, accounting for at least nine out of ten patients with diabetes. Although it can occur in younger people, it most often begins when people are over 40 years of age.

Symptoms of type 2 diabetes
In its early stages, type 2 diabetes often has no symptoms. When symptoms do occur, they may come on gradually and be very subtle. They include:

  • Problems with sexual function
  • Slow healing of cuts or sores
  • Increased hunger and thirst
  • Numbness or tingling in hands or feet
Causes of type 2 diabetes
No one knows the exact cause of type 2 diabetes. We do know that it is more likely to occur in people who:1 Since the tendency to develop type 2 diabetes may be inherited, any member of your family (mother, father, sister, brother, children) who has three or more of the above symptoms should be tested for diabetes. Also, regular exercise and managing your weight may help prevent or delay some cases of type 2 diabetes.

Treatment of type 2 diabetes
Diabetes is different for each person. Depending on the stage of your diabetes and your body's response to certain therapies, your healthcare provider may prescribe one or more treatments. For example, you may be able to control your diabetes with diabetes pills alone or you may need more than one pill to control your blood sugar. For others, it may make more sense to start with insulin instead of pills.

Diabetes is a disease that changes over time, and because of this, your diabetes treatment may also need to change to keep your blood sugar level in good control. Early in the treatment of type 2 diabetes, pills may work just fine to control your blood sugar. But over time, the pills may not continue to work as well. In fact, most people with type 2 diabetes will eventually need to take insulin to control their blood sugar levels.

Reference:
1. ADA National Diabetes Fact Sheet, 2005. Available at http://www.diabetes.org/diabetes-statistics.jsp. Accessed March 3, 2006.
Important Safety Information
Humalog, Humalog Mix75/25, and Humalog Mix50/50 are for use in patients with diabetes to control high blood sugar. Humalog should be used with a longer-acting insulin, except when used in combination with sulfonylureas in patients with type 2 diabetes.

Humalog insulins are contraindicated during episodes of hypoglycemia and in patients sensitive to Humalog or one of its excipients. The safety and effectiveness of Humalog in patients less than 3 years of age have not been established. Safety and effectiveness of Humalog Mix75/25 and Humalog Mix50/50 in patients less than 18 years of age have not been established. There are no clinical studies of the use of Humalog insulins in pregnancy or nursing mothers.

Potential side effects associated with the use of all insulins include low blood sugar, weight gain, low blood potassium, changes in fat tissue at the site of injection, and allergic reactions, both general and local. Humalog Mix75/25 and Humalog Mix50/50 should not be mixed with another insulin. Starting or changing insulin therapy should be done cautiously and only under medical supervision.

Humalog insulins are available by prescription only. See the Humalog, Humalog Mix75/25, and Humalog Mix50/50 Patient Product Information for important facts about these products.

Humalog is a registered trademark of Eli Lilly and Company. Humalog Mix75/25 and Humalog Mix50/50 are trademarks of Eli Lilly and Company.



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