Understanding the Side Effects of Mixture Insulin
Low blood sugar (hypoglycemia)
This condition occurs when there is not enough glucose in the blood. Mild to moderate hypoglycemia can be treated by eating foods or drinks that contain sugar. More severe hypoglycemia may require an injection of glucagon. For information on the causes and symptoms of hypoglycemia, as well as guidance on treating hypoglycemia, see low blood sugar.
Because low blood sugar feels different to different people, it is important to learn to recognize your own particular symptoms. If you have a blood sugar reading below 60 mg/dL and aren't experiencing any of the symptoms, you still need immediate treatment. Make sure to notify your doctor of this event. Remember that most lows can be prevented when you know what causes them.
Hyperglycemia and diabetic ketoacidosis (DKA)
Hyperglycemia occurs when there is too much glucose in the blood, and may develop if your body has too little insulin. A number of medicines (including over-the-counter medicines) may increase your blood sugar. Talk to your healthcare provider to find out what is safe for you. For details about the causes and symptoms of hyperglycemia, as well as guidance on treating and managing this condition, see high blood sugar.
Ketoacidosis
Ketoacidosis is a serious condition that usually occurs only in people with type 1 diabetes. If it is not treated, ketoacidosis can lead to nausea, vomiting, dehydration, loss of consciousness, or even death. Ketoacidosis can develop very quickly, especially when you're sick with a cold, flu or any other kind of infection, or during periods of severe stress. That's why it's so important to check your blood sugar and urine ketone levels several times a day when you are sick and seek medical attention immediately if ketone levels are high.
For more detailed information about ketoacidosis, see high blood sugar.
Lipodystrophy
In rare cases, injecting insulin can result in lipoatrophy (depressions in the skin) or lipohypertrophy (enlargement or thickening of the tissue beneath the skin). If you notice either of these conditions, consult your doctor. A change in your injection technique may help solve the problem.
Humalog Mix75/25 and Humalog Mix50/50 are available by prescription only. See Humalog Mix75/25 and Humalog Mix50/50 Patient Information for important facts about these products.
Important Safety Information
Humalog, Humalog Mix75/25, and Humalog Mix50/50 are for use in patients with diabetes to control high blood sugar. Humalog should be used with a longer-acting insulin, except when used in combination with sulfonylureas in patients with type 2 diabetes.
Humalog insulins are contraindicated during episodes of hypoglycemia and in patients sensitive to Humalog or one of its excipients. The safety and effectiveness of Humalog in patients less than 3 years of age have not been established. Safety and effectiveness of Humalog Mix75/25 and Humalog Mix50/50 in patients less than 18 years of age have not been established. There are no clinical studies of the use of Humalog insulins in pregnancy or nursing mothers.
Potential side effects associated with the use of all insulins include low blood sugar, weight gain, low blood potassium, changes in fat tissue at the site of injection, and allergic reactions, both general and local. Humalog Mix75/25 and Humalog Mix50/50 should not be mixed with another insulin. Starting or changing insulin therapy should be done cautiously and only under medical supervision.
Humalog insulins are available by prescription only. See the Humalog, Humalog Mix75/25, and Humalog Mix50/50 Patient Product Information for important facts about these products.
Humalog is a registered trademark of Eli Lilly and Company. Humalog Mix75/25 and Humalog Mix50/50 are trademarks of Eli Lilly and Company.
Humalog, Humalog Mix75/25, and Humalog Mix50/50 are for use in patients with diabetes to control high blood sugar. Humalog should be used with a longer-acting insulin, except when used in combination with sulfonylureas in patients with type 2 diabetes.
Humalog insulins are contraindicated during episodes of hypoglycemia and in patients sensitive to Humalog or one of its excipients. The safety and effectiveness of Humalog in patients less than 3 years of age have not been established. Safety and effectiveness of Humalog Mix75/25 and Humalog Mix50/50 in patients less than 18 years of age have not been established. There are no clinical studies of the use of Humalog insulins in pregnancy or nursing mothers.
Potential side effects associated with the use of all insulins include low blood sugar, weight gain, low blood potassium, changes in fat tissue at the site of injection, and allergic reactions, both general and local. Humalog Mix75/25 and Humalog Mix50/50 should not be mixed with another insulin. Starting or changing insulin therapy should be done cautiously and only under medical supervision.
Humalog insulins are available by prescription only. See the Humalog, Humalog Mix75/25, and Humalog Mix50/50 Patient Product Information for important facts about these products.
Humalog is a registered trademark of Eli Lilly and Company. Humalog Mix75/25 and Humalog Mix50/50 are trademarks of Eli Lilly and Company.
