Questions About Insulin

About Mixture Insulins
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Glossary
Rapid-acting Insulin
Insulin that starts to work quickly (usually within 15 minutes), with its peak activity (strongest effect) lasting only a few hours. Generally, rapid-acting insulin, like Humalog, is a mealtime insulin (except when used in an external insulin pump).
Glossary
Longer-acting Insulin
Insulin that takes longer to work than rapid-acting insulin, but its duration of action (how long it works) can last up to 20 hours. Humalog Mix75/25 and Humalog Mix50/50 both contain longer-acting insulin to help keep blood glucose stable between meals.
For people new to insulin, mixture insulin may be a good option to help manage blood sugar levels throughout the day and at meals. Mixture insulin contains both rapid-acting and longer-acting insulin to do this. One of the leaders in diabetes care for more than 80 years, Lilly offers two types of mixture insulins. Humalog Mix75/25 and Humalog Mix50/50 are for use in patients with diabetes, to control high blood sugar.

KwikPen This section will help you understand mixture insulin, from its benefits to how it is taken. Only your doctor can know which insulin might be best for you or your loved one, so be sure to take advantage of the Questions for Your Healthcare Team to discuss your individual needs.

It's in the mix
Wondering what the numbers "75/25" and "50/50" mean in the products' names? They refer to the percentages of longer-acting insulin and rapid-acting insulin in the mix. Humalog Mix75/25 is a mixture of 75% longer-acting insulin (insulin lispro protamine suspension) and 25% rapid-acting insulin (insulin lispro). Similarly, Humalog Mix50/50 is a mixture of 50% longer-acting insulin and 50% rapid-acting insulin. Only your doctor can tell you which mixture insulin is right for you.

Humalog Mix75/25 and Humalog Mix50/50 are available by prescription only. See Humalog Mix75/25 and Humalog Mix50/50 Patient Information for important facts about these products.

Important Safety Information
Humalog, Humalog Mix75/25, and Humalog Mix50/50 are for use in patients with diabetes to control high blood sugar. Humalog should be used with a longer-acting insulin, except when used in combination with sulfonylureas in patients with type 2 diabetes.

Humalog insulins are contraindicated during episodes of hypoglycemia and in patients sensitive to Humalog or one of its excipients. The safety and effectiveness of Humalog in patients less than 3 years of age have not been established. Safety and effectiveness of Humalog Mix75/25 and Humalog Mix50/50 in patients less than 18 years of age have not been established. There are no clinical studies of the use of Humalog insulins in pregnancy or nursing mothers.

Potential side effects associated with the use of all insulins include low blood sugar, weight gain, low blood potassium, changes in fat tissue at the site of injection, and allergic reactions, both general and local. Humalog Mix75/25 and Humalog Mix50/50 should not be mixed with another insulin. Starting or changing insulin therapy should be done cautiously and only under medical supervision.

Humalog insulins are available by prescription only. See the Humalog, Humalog Mix75/25, and Humalog Mix50/50 Patient Product Information for important facts about these products.

Humalog is a registered trademark of Eli Lilly and Company. Humalog Mix75/25 and Humalog Mix50/50 are trademarks of Eli Lilly and Company.



Humalog Patient Information | Humalog Mix75/25 Patient Information | Humalog Mix50/50 Patient Information | Important Safety Information