Humalog in Insulin Pumps
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An insulin pump is an external device that continuously delivers rapid-acting insulin to your body through a tiny tube placed under the skin. About the size of a cell phone, it can be hidden under clothing or worn on your waistband. This section will provide an overview of insulin pump basics, as well as information specific to the use of Humalog in insulin pumps.

How an insulin pump works
Insulin pumps are programmed by the user to continuously deliver tiny doses of rapid-acting insulin between meals or overnight. This is called your basal insulin. At meals, the user programs an extra dose of insulin, called a "bolus," to cover food. This insulin regimen most closely mimics how a healthy pancreas works in a person without diabetes. As a result, an insulin pump can help give you more flexibility around exercise and other variable activities that affect your insulin needs.

Your doctor or diabetes educator will train you on how to use an insulin pump. While an insulin pump can offer many lifestyle benefits, you have to be committed to "intensive insulin therapy" to make it successful. Part of this commitment is checking your blood sugar frequently to know how much insulin to program or to catch any disruptions in insulin delivery.

Insulin Pump Therapy

Humalog in insulin pumps
Humalog is approved for use in external insulin pumps. It was the first rapid-acting insulin approved for use in external insulin pumps, and 65% of patients surveyed using an insulin pump use Humalog (2004).1 In people with type 1 diabetes using an insulin pump, Humalog may help lower A1Cs compared to regular human insulin.2

When used in an external insulin pump, Humalog should not be diluted or mixed with any other insulin. Patients are advised to carefully follow the insulin pump manufacturer's instructions for use of Humalog in an external insulin pump.

Humalog is available by prescription only. See Humalog Patient Information for important facts about this product.


In 12-month clinical studies, A1C did not differ between patients treated with regular human insulin and those treated with Humalog.

References:
1. NOP World Health. Roper Survey of the US Diabetes Patient Market 2004.
2. Humalog Prescribing Information. Indianapolis, IN: Eli Lilly and Company; 2004.
Important Safety Information
Humalog, Humalog Mix75/25, and Humalog Mix50/50 are for use in patients with diabetes to control high blood sugar. Humalog should be used with a longer-acting insulin, except when used in combination with sulfonylureas in patients with type 2 diabetes.

Humalog insulins are contraindicated during episodes of hypoglycemia and in patients sensitive to Humalog or one of its excipients. The safety and effectiveness of Humalog in patients less than 3 years of age have not been established. Safety and effectiveness of Humalog Mix75/25 and Humalog Mix50/50 in patients less than 18 years of age have not been established. There are no clinical studies of the use of Humalog insulins in pregnancy or nursing mothers.

Potential side effects associated with the use of all insulins include low blood sugar, weight gain, low blood potassium, changes in fat tissue at the site of injection, and allergic reactions, both general and local. Humalog Mix75/25 and Humalog Mix50/50 should not be mixed with another insulin. Starting or changing insulin therapy should be done cautiously and only under medical supervision.

Humalog insulins are available by prescription only. See the Humalog, Humalog Mix75/25, and Humalog Mix50/50 Patient Product Information for important facts about these products.

Humalog is a registered trademark of Eli Lilly and Company. Humalog Mix75/25 and Humalog Mix50/50 are trademarks of Eli Lilly and Company.



Humalog Patient Information | Humalog Mix75/25 Patient Information | Humalog Mix50/50 Patient Information | Important Safety Information