Humalog in Children
Glossary
Insulin
A hormone produced in the pancreas by beta cells, which is necessary for glucose (blood sugar) to be able to enter certain cells of the body and be used for energy.
A hormone produced in the pancreas by beta cells, which is necessary for glucose (blood sugar) to be able to enter certain cells of the body and be used for energy.
Glossary
Type 1 Diabetes
A condition characterized by high blood glucose levels caused by a lack of insulin production. Type 1 diabetes occurs when the body's immune system destroys the cells in the pancreas that produce insulin. The pancreas then produces little or no insulin. Type 1 diabetes develops most often in young people but can appear in adults and affects 10% of people living with diabetes. People with type 1 diabetes must take insulin daily to sustain life.
A condition characterized by high blood glucose levels caused by a lack of insulin production. Type 1 diabetes occurs when the body's immune system destroys the cells in the pancreas that produce insulin. The pancreas then produces little or no insulin. Type 1 diabetes develops most often in young people but can appear in adults and affects 10% of people living with diabetes. People with type 1 diabetes must take insulin daily to sustain life.
Glossary
Blood Sugar Levels
The amount of sugar (glucose) in a given amount of blood. It is reported as the number of milligrams of glucose in a deciliter of blood, or mg/dL.
The amount of sugar (glucose) in a given amount of blood. It is reported as the number of milligrams of glucose in a deciliter of blood, or mg/dL.
Glossary
Hypoglycemia
Also called low blood sugar. Symptoms may include sweating, trembling, hunger, dizziness, moodiness, confusion, and blurred vision.
Also called low blood sugar. Symptoms may include sweating, trembling, hunger, dizziness, moodiness, confusion, and blurred vision.
Glossary
Dose
The amount of a medicine to be taken within a given period.
The amount of a medicine to be taken within a given period.
Help with lows overnight
Humalog may also help reduce the risk of low blood sugar overnight compared to regular insulin for children with type 1 diabetes.2 Low blood sugar overnight can cause parents to lose sleep as they worry and monitor their child's blood sugar.

Humalog insulin delivery options
Humalog can be injected using a traditional syringe and vial, and it's approved for use in an external insulin pump. Humalog is also available in cartridges for use in the HumaPen® LUXURA™ HD, a reusable insulin pen that doses in half-unit increments from 1 to 30 units for parents and caregivers of children with diabetes. The design and features of HumaPen LUXURA HD enable you to deliver a precise dose.
After initial set-up, you simply dial your child's dose by turning the dose knob in half-unit increments after the first unit.
If you dial too much, simply turn the knob back to the correct dose.
Before use, patients and their caregivers are advised to carefully read the Pen User Manual enclosed in the Pen box and the Patient Information provided with the Humalog insulin cartridges.
For more information about children and insulin, see our Resources section.
Humalog is available by prescription only. See Humalog Patient Information for important facts about this product.
HumaPen LUXURA HD is available by prescription only.
The clinical value of improving blood sugar after meals has not been established. In 12-month clinical studies, A1C did not
differ between patients treated with regular human insulin and those treated with Humalog. Patients with type 1 diabetes
also require a longer-acting insulin to get optimal blood sugar control.
References:
1. Deeb LC, Holcombe JH, Brunelle R, et al. Insulin lispro lowers postprandial glucose in prepubertal children with diabetes. Pediatrics. 2001;108(5):1175-9.
2. Holcombe JH, Zalani S, Arora VK, et al. Comparison of insulin lispro with regular human insulin for the treatment of type 1 diabetes in adolescents. Clin Ther. 2002;24(4):629-38.
3. Silverstein J, Klingensmith G, Copeland K, et al. Care of children and adolescents with type 1 diabetes: a statement of the American Diabetes Association. Diabetes Care. 2005;28(1):186-2212.
1. Deeb LC, Holcombe JH, Brunelle R, et al. Insulin lispro lowers postprandial glucose in prepubertal children with diabetes. Pediatrics. 2001;108(5):1175-9.
2. Holcombe JH, Zalani S, Arora VK, et al. Comparison of insulin lispro with regular human insulin for the treatment of type 1 diabetes in adolescents. Clin Ther. 2002;24(4):629-38.
3. Silverstein J, Klingensmith G, Copeland K, et al. Care of children and adolescents with type 1 diabetes: a statement of the American Diabetes Association. Diabetes Care. 2005;28(1):186-2212.
Important Safety Information
Humalog, Humalog Mix75/25, and Humalog Mix50/50 are for use in patients with diabetes to control high blood sugar. Humalog should be used with a longer-acting insulin, except when used in combination with sulfonylureas in patients with type 2 diabetes.
Humalog insulins are contraindicated during episodes of hypoglycemia and in patients sensitive to Humalog or one of its excipients. The safety and effectiveness of Humalog in patients less than 3 years of age have not been established. Safety and effectiveness of Humalog Mix75/25 and Humalog Mix50/50 in patients less than 18 years of age have not been established. There are no clinical studies of the use of Humalog insulins in pregnancy or nursing mothers.
Potential side effects associated with the use of all insulins include low blood sugar, weight gain, low blood potassium, changes in fat tissue at the site of injection, and allergic reactions, both general and local. Humalog Mix75/25 and Humalog Mix50/50 should not be mixed with another insulin. Starting or changing insulin therapy should be done cautiously and only under medical supervision.
Humalog insulins are available by prescription only. See the Humalog, Humalog Mix75/25, and Humalog Mix50/50 Patient Product Information for important facts about these products.
Humalog is a registered trademark of Eli Lilly and Company. Humalog Mix75/25 and Humalog Mix50/50 are trademarks of Eli Lilly and Company.
Humalog, Humalog Mix75/25, and Humalog Mix50/50 are for use in patients with diabetes to control high blood sugar. Humalog should be used with a longer-acting insulin, except when used in combination with sulfonylureas in patients with type 2 diabetes.
Humalog insulins are contraindicated during episodes of hypoglycemia and in patients sensitive to Humalog or one of its excipients. The safety and effectiveness of Humalog in patients less than 3 years of age have not been established. Safety and effectiveness of Humalog Mix75/25 and Humalog Mix50/50 in patients less than 18 years of age have not been established. There are no clinical studies of the use of Humalog insulins in pregnancy or nursing mothers.
Potential side effects associated with the use of all insulins include low blood sugar, weight gain, low blood potassium, changes in fat tissue at the site of injection, and allergic reactions, both general and local. Humalog Mix75/25 and Humalog Mix50/50 should not be mixed with another insulin. Starting or changing insulin therapy should be done cautiously and only under medical supervision.
Humalog insulins are available by prescription only. See the Humalog, Humalog Mix75/25, and Humalog Mix50/50 Patient Product Information for important facts about these products.
Humalog is a registered trademark of Eli Lilly and Company. Humalog Mix75/25 and Humalog Mix50/50 are trademarks of Eli Lilly and Company.

























