Meet Debra

  • Currently takes an average of 15 units of mealtime insulin at each meal and goes through more than 4 mealtime insulin pens every month
  • Does her best to plan for her busy schedule and manage her diabetes
  • There may be times when her plans change unexpectedly, and despite her best planning she doesn’t have enough mealtime insulin with her
  • During her appointments, she may talk about her busy schedule, but she may not tell you about the times she missed a dose because she didn’t have enough mealtime insulin with her

*As with other pens, you should always carry an extra pen.

Hypothetical patient.

Humalog® U-200 KwikPen® is the first and only mealtime insulin pen that:

  • Is bioequivalent* to Humalog® U-100; therefore, you should expect similar efficacy as Humalog U-1001,2
  • Contains 600 units of rapid-acting insulin,1 compared with the 300 units in a U-100 pen
  • Contains concentrated 200 units/mL insulin1
  • Is the same size1 and familiar design as Humalog® U-100 KwikPen®

*As determined by area under the curve and maximum concentration.

Select Safety Information

Humalog, Humalog Mix75/25, and Humalog Mix50/50 are contraindicated during episodes of hypoglycemia and in patients who are hypersensitive to Humalog or any of its excipients.

With Humalog U-200 KwikPen, patients can have a mealtime insulin pen that lasts longer between pen changes*†

  • Fewer pen changes every month*†
  • May help patients worry less about running out of insulin when plans change unexpectedly†‡

How often a patient changes pens if they need 15 units, 3 times a day

Humalog U-100 KwikPen - Change About every 7 days; Humalog U-200 KwikPen - Change About every 14 days

*Once opened, Humalog prefilled pens should be thrown away after 28 days, even if insulin remains.

As compared with U-100 mealtime insulin pens.

As with other pens, you should always carry an extra pen.

Delivers the same dose in half the liquid volume of Humalog U-100 KwikPen1

Dosing for Humalog U-100 KwikPen - Equal Units - Dosing for Humalog U-200 KwikPen

Humalog U-200 KwikPen contains U-200 mealtime insulin, which is twice the concentration of Humalog U-100.1

Select Safety Information

Never share a Humalog, Humalog Mix75/25, or Humalog Mix50/50 KwikPen, cartridge, reusable pen compatible with Lilly 3 mL cartridges, or syringe between patients as it poses a risk for transmission of blood-borne pathogens.

Humalog U-200 KwikPen is the same size as, and feels and operates like a Humalog U-100 KwikPen*

Humalog U-100 KwikPen - Humalog U-200 KwikPen - dosing instructions
  • Same size1 and familiar design
  • No dose calculations or conversions are required
  • Dialing 1 unit delivers 1 unit of mealtime insulin
  • Both pens contain 3 mL of liquid

*Please see Instructions for Use included with the pen.

Writing the prescription

  • When prescribing for your patients, be sure to specify the full product name: Humalog 200 units/mL KwikPen
  • When using EMR to prescribe Humalog U-200 KwikPen, use the chart below as a guide, based on the requirements of your EMR*
hcp EMR dosing chart

*Assumes a 30-day month and that patient's product is dispensed in full packs.

hcp kwikpen

Savings card assistance

Savings card assistance is available so eligible commercially insured patients can pay as little as $25 a month*

STEP 1: Request savings card(s)


* See full terms and conditions for eligibility.


Download and print cards


Pay as little as $25 per prescription*

*Applies to each of your first 24 prescriptions. Lilly pays up to $100 per month. Other terms and restrictions apply.

If you have questions, we’re here to help. Call The Lilly Answers Center at 1-800-LillyRx (1-800-545-5979).

This offer is invalid for patients whose prescription claims are eligible to be reimbursed, in whole or in part, by any governmental program.

Be sure to activate your card by going to prior to taking it to the pharmacy.

RxBin: 601341 RxPCN: OHCP
RxGRP: OH6801051 RxID: [XXXXXXX] SUF: 01

Expiration Date: 12/31/2018

Pharmacist Instructions:

This card must be accompanied by a valid prescription for Humalog U-200 KwikPen. This offer is eligible for patients with commercial insurance who do not receive government reimbursement for their prescriptions. If the patient qualifies per the terms of the offer, submit as a secondary claim to OPUS Health using BIN: 601341 and using the Coordination of Benefits fields with coverage code type 08. One card per patient. By accepting this offer you certify that you understand and agree to comply with the offer terms set forth herein. If you are required to do so under the terms of your third-party payer contracts or as otherwise required by law, you should notify the affected third-party payer of your redemption of this offer. Please return card to patient after claim is processed. Pharmacists with questions, please call OPUS Health at 1-800-364-4767.

Eligibility Requirements:

By using the Humalog U-200 KwikPen savings card ("Card"), you attest that you meet the eligibility criteria and will comply with the Terms and Conditions described below. Offer void where prohibited by law. This offer is invalid for patients without commercial insurance coverage or those whose prescription claims for Humalog U-200 KwikPen are eligible to be reimbursed, in whole or in part, by any governmental program, including, without limitation, Medicaid, Medicare, Medicare Part D, Medigap, DOD, VA, TRICARE/CHAMPUS, or any State Patient or Pharmaceutical Assistance Program. If you live in Massachusetts, the Card expires on the earlier of: (i) the expiration date of this Card (December 31, 2018); (ii) the date an AB rated generic equivalent becomes available; or (iii) July 1, 2017 absent a change in Mass. state law. Available only in the US and Puerto Rico. By accepting this offer, you agree that if you are required to do so under the terms of your insurance coverage for this prescription or are otherwise required to do so by law, you should notify your insurance carrier of your redemption of this Card. This offer is not valid with any other program, discount, incentive, or similar offer involving Humalog U-200 KwikPen. It is prohibited for any person to sell, purchase or trade; or to offer to sell, purchase or trade, or to counterfeit this Card. This offer may be terminated, rescinded, revoked or amended by Lilly USA, LLC at any time without notice. This Card is not health insurance. This Card expires on 12/31/2018.

PP-HI-US-0672 03/2016 ©Lilly USA, LLC 2016. All rights reserved.

Humalog® and Humalog® KwikPen® are registered trademarks owned or licensed by Eli Lilly and Company, its subsidiaries, or affiliates, and are available by prescription only.

STEP 2: Patient support

We are committed to helping you help patients get started successfully

  • Please remind patients that the first step is activating their savings card
  • LEARN MORE about Humalog U-200 KwikPen savings card support and eligibility.

    Select Safety Information

    Changes in insulin regimen may affect glycemic control and predispose patients to hypoglycemia and hyperglycemia. Changes should be made cautiously and the frequency of blood glucose monitoring should be increased.

    Humalog U-200 is bioequivalent* to Humalog U-1001

    Humalog U-200 was bioequivalent to Humalog U-100 after subcutaneous administration of a single 20-unit dose in healthy subjects. Time to maximum concentration was also similar between formulations.1

    *As determined by area under the curve and maximum concentration.

    Humalog U-200 exhibits pharmacokinetic and pharmacodynamic properties comparable to Humalog U-100.2,3

    Similar pharmacokinetic properties*2

    Humalog U-200 - Similar pharmacokinetic properties - Humalog U-200 Bioequivalence

    *Determined after subcutaneous administration of 20 units to healthy subjects. Time to maximum drug concentration was also similar between formulations.

    Similar pharmacodynamic properties3

    Humalog U-200 - Similar pharmacodynamic properties - Humalog U-200 Bioequivalent


    1. Humalog [Prescribing Information]. Indianapolis, IN: Lilly USA, LLC; 2015.
    2. Data on file, Lilly Research Laboratories: HI20150521A.
    3. Data on file, Lilly Research Laboratories: HI20150526A.