Patient tutorial shows how to use HumaPen MEMOIR.
Questions About HumaPen® MEMOIR™
- Do needles come with the Pen? What size should I recommend for my patients?
- What if the Pen does not turn on?
- What if I want to turn the Pen off?
- What if a part of the Pen display is missing or stays on all the time?
- What if insulin does not come out when the Pen is primed?
- What if there is an air bubble in the cartridge after the Pen is primed?
- What if insulin comes out when the Pen is dialed backwards?
- What if the dose knob does not go to 0 when my patient injects their dose?
- What if it is difficult to push down the dose knob when injecting?
- Why must the injection button be held down for five seconds after the injection?
Do needles come with the Pen? What size should I recommend for my patients?
HumaPen MEMOIR is suitable for use with Becton, Dickinson and Company's insulin pen needles (sold separately). There are a variety of pen needles currently available.
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What if the Pen does not turn on?
Make sure you are pressing the ON button. If the Pen does not turn on, contact the Lilly Answers Center at 1-800-LillyRx (1-800-545-5979).
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What if I want to turn the Pen off?
To prevent the Pen from accidentally being turned off during an injection, there is no OFF button. The Pen will not turn off unless the display is in READY MODE. The Pen will automatically turn off after 30 seconds of inactivity.
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What if a part of the Pen display is missing or stays on all the time?
The display is not working correctly. Do not use the Pen. Contact the Lilly Answers Center at 1-800-LillyRx (1-800-545-5979).
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What if insulin does not come out when the Pen is primed?
The needle may be clogged, the cartridge holder may not be completely screwed on, or the foot of the injection screw may not be against the cartridge plunger. You may not be able to see the foot of the injection screw, but repeating the priming step will move it to touch the plunger.
Priming until you see a stream of insulin will ensure that the foot of the injection screw is against the cartridge plunger.
- Repeat the priming steps until a stream of insulin is seen.
- If you do not see a stream of insulin after several attempts, attach a new needle.
- Repeat the priming steps until a stream of insulin is seen.
- If you are still unable to get insulin flowing out of the needle, do NOT use the Pen. Contact the Lilly Answers Center at 1-800-LillyRx (1-800-545-5979).
What if there is an air bubble in the cartridge after the Pen is primed?
Hold the Pen with the needle facing upwards and pointing away from your face. Tap the insulin cartridge holder gently with your finger so any air bubbles can collect near the top. Repeat the priming step. A small air bubble may remain in the cartridge after the completion of the priming step. If you have properly primed the Pen, this small air bubble will not affect the insulin dose.
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What if insulin comes out when the Pen is dialed backwards?
The dose knob may have been accidentally pushed when dialing backwards. To avoid this, do NOT push the dose knob when dialing backwards. Only push the dose knob when injecting.
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What if the dose knob does not go to 0 when my patient injects their dose?
The cartridge may not have had enough insulin for the entire dose. The number in the display window is the amount your patient did NOT receive. To get the rest of the dose: Dial down to 0. This will save the first injection in dose memory and return the Pen to READY MODE. Next, change the insulin cartridge, prime the Pen, and inject only the dose amount that was not received. Please note that the dose memory will record this as a separate dose.
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What if it is difficult to push down the dose knob when injecting?
- Pressing the dose knob down quickly may make the button harder to push. Pressing the dose knob more slowly may make it easier.
- Pressing on the side of the dose knob may make it harder to inject. Be sure to press straight in on the dose knob.
- The force required to push the dose knob depends on the needle diameter.
- The dose knob may become harder to push if foreign material (dirt, dust), insulin, or other liquids get inside the Pen. Replace the Pen if the dose knob gets too hard to push.
Why must the injection button be held down for five seconds after the injection?
After the injection button is fully depressed, it takes a few seconds to completely expel the insulin dose, primarily due to the elasticity of the rubber plunger. As with all Lilly insulin pens, five seconds is recommended as the appropriate time needed to ensure full dose delivery.
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HumaPen MEMOIR is available by prescription only.
Important Safety Information
Humalog insulins are contraindicated during episodes of hypoglycemia and in patients sensitive to Humalog or one of its excipients. The safety and effectiveness of Humalog in patients less than 3 years of age have not been established. Safety and effectiveness of Humalog Mix75/25 and Humalog Mix50/50 in patients less than 18 years of age have not been established. There are no adequate and well-controlled clinical studies of the use of Humalog in pregnant or nursing mothers.
Potential side effects associated with the use of all insulins include hypoglycemia, weight gain, hypokalemia, lipodystrophy, and hypersensitivity. Because of the difference in action of Humalog, care should be taken in patients in whom these conditions may be clinically relevant (e.g., those who are fasting, have autonomic neuropathy or renal impairment, are using potassium-lowering drugs, or taking drugs sensitive to serum potassium level). Patients should be advised not to mix Humalog Mix75/25 or Humalog Mix50/50 with another insulin. Starting or changing insulin therapy should be done cautiously and only under medical supervision.
When used in an external insulin pump, Humalog should not be diluted or mixed with any other insulin. Humalog Mix75/25 and Humalog Mix50/50 are not indicated for use in external insulin pumps.
Humalog differs from regular human insulin by its rapid onset of action, as well as a shorter duration of activity. Therefore, Humalog and Humalog Mixtures should be given within 15 minutes before a meal. Humalog can also be given immediately after a meal. The short duration of action of Humalog means that patients such as those with type 1 diabetes, whose basal insulin levels are inadequate, will also require a longer-acting insulin to give optimal glucose control (except when using an insulin pump).
Clinical studies comparing Humalog Mix75/25 with human insulin mixtures did not show a difference in the overall rate of hypoglycemia between the two treatments. The overall rate of hypoglycemia did not differ between type 1 and type 2 patients treated with Humalog, as compared with regular human insulin. The lower rate of hypoglycemia with Humalog may be related to higher nocturnal blood glucose levels, as reflected by a small increase in the mean fasting blood glucose levels.
The clinical significance of improvement in postmeal hyperglycemia has not been established. In 12-month clinical studies, A1C did not differ between patients treated with regular human insulin and those treated with Humalog.
Humalog, Humalog Mix75/25, and Humalog Mix50/50 are available by prescription only.
For other important safety information and prescribing considerations, please see Humalog, Humalog Mix75/25, and Humalog Mix50/50 Prescribing Information.
Humalog is a registered trademark of Eli Lilly and Company. Humalog Mix75/25 and Humalog Mix50/50 are trademarks of Eli Lilly and Company.
Humalog insulins are contraindicated during episodes of hypoglycemia and in patients sensitive to Humalog or one of its excipients. The safety and effectiveness of Humalog in patients less than 3 years of age have not been established. Safety and effectiveness of Humalog Mix75/25 and Humalog Mix50/50 in patients less than 18 years of age have not been established. There are no adequate and well-controlled clinical studies of the use of Humalog in pregnant or nursing mothers.
Potential side effects associated with the use of all insulins include hypoglycemia, weight gain, hypokalemia, lipodystrophy, and hypersensitivity. Because of the difference in action of Humalog, care should be taken in patients in whom these conditions may be clinically relevant (e.g., those who are fasting, have autonomic neuropathy or renal impairment, are using potassium-lowering drugs, or taking drugs sensitive to serum potassium level). Patients should be advised not to mix Humalog Mix75/25 or Humalog Mix50/50 with another insulin. Starting or changing insulin therapy should be done cautiously and only under medical supervision.
When used in an external insulin pump, Humalog should not be diluted or mixed with any other insulin. Humalog Mix75/25 and Humalog Mix50/50 are not indicated for use in external insulin pumps.
Humalog differs from regular human insulin by its rapid onset of action, as well as a shorter duration of activity. Therefore, Humalog and Humalog Mixtures should be given within 15 minutes before a meal. Humalog can also be given immediately after a meal. The short duration of action of Humalog means that patients such as those with type 1 diabetes, whose basal insulin levels are inadequate, will also require a longer-acting insulin to give optimal glucose control (except when using an insulin pump).
Clinical studies comparing Humalog Mix75/25 with human insulin mixtures did not show a difference in the overall rate of hypoglycemia between the two treatments. The overall rate of hypoglycemia did not differ between type 1 and type 2 patients treated with Humalog, as compared with regular human insulin. The lower rate of hypoglycemia with Humalog may be related to higher nocturnal blood glucose levels, as reflected by a small increase in the mean fasting blood glucose levels.
The clinical significance of improvement in postmeal hyperglycemia has not been established. In 12-month clinical studies, A1C did not differ between patients treated with regular human insulin and those treated with Humalog.
Humalog, Humalog Mix75/25, and Humalog Mix50/50 are available by prescription only.
For other important safety information and prescribing considerations, please see Humalog, Humalog Mix75/25, and Humalog Mix50/50 Prescribing Information.
Humalog is a registered trademark of Eli Lilly and Company. Humalog Mix75/25 and Humalog Mix50/50 are trademarks of Eli Lilly and Company.
