About Humalog KwikPen

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Mealtime insulin doesn't have to throw your whole life out of sync. One way to take your Humalog® mealtime insulin is with Humalog® KwikPen. Prefilled with Humalog, Humalog KwikPen can help you fit mealtime insulin into your day.

Humalog KwikPen Logo
  • It looks like a pen and is the size of a marker
  • It's truly portable, so you can take it just about anywhere
  • It allows you to discreetly dose
  • It's kept outside the refrigerator after first use

In-use Humalog KwikPen should be stored at room temperature, below 86°F (30°C), and must be used within 28 days or be discarded, even if it still contains Humalog. Talk to your healthcare provider to find out if Humalog KwikPen is right for you.

Pen in depth

Before use, patients should carefully read the Instructions for Use for Humalog KwikPen. For full storage and disposal information for Humalog KwikPen, please see the Patient Information.

Pens and needles are for single-patient use only and should not be shared, even in healthcare facilities, as infection or disease can be spread from one person to another.

Do not withdraw insulin from the pen using a syringe.

Humalog Mix75/25 KwikPen and Humalog Mix50/50 KwikPen

The pen also comes prefilled with Humalog® Mix75/25 and Humalog® Mix50/50 premixed insulins. In-use Humalog® Mix75/25 KwikPen and Humalog® Mix50/50 KwikPen should be stored at room temperature, below 86°F (30°C). Humalog Mix75/25 KwikPen and Humalog Mix50/50 KwikPen must be used within 10 days or be discarded, even if they still contain insulin. Talk to your healthcare provider to find out if the pen is right for you.

Humalog KwikPen 75/25 Mix Humalog KwikPen 75/25 Pen
Humalog KwikPen 50/50 Mix Humalog KwikPen 50/50 Pen

Before use, patients should carefully read the Instructions for Use for Humalog Mix75/25 KwikPen or Humalog Mix50/50 KwikPen. For full storage and disposal information, please see the Patient Information that comes with the pen.

Pens and needles are for single-patient use only and should not be shared, even in healthcare facilities, as infection or disease can be spread from one person to another.

Do not withdraw insulin from the pen using a syringe.

Who should use Humalog, Humalog Mix75/25, or Humalog Mix50/50?

Humalog is used to treat people with diabetes for the control of blood sugar. Humalog Mix75/25 and Humalog Mix50/50 are used to treat adults with diabetes for the control of high blood sugar. These insulins contain 100 units per mL.

Humalog is used to treat people with diabetes for the control of blood sugar. Humalog Mix75/25 (75% insulin lispro protamine suspension, 25% insulin lispro injection [rDNA origin]), and Humalog Mix50/50 (50% insulin lispro protamine suspension, 50% insulin lispro injection [rDNA origin]) are used to treat adults with diabetes for the control of high blood sugar. These insulins contain 100 units per mL.

What is some select safety Information I should know about Humalog, Humalog Mix75/25, and Humalog Mix50/50?

  • Do not take Humalog, Humalog Mix75/25, or Humalog Mix50/50 if your blood sugar is too low (hypoglycemia) or if you are allergic to insulin lispro or any of the ingredients in these insulins.
  • Do not change the insulin you use without talking to your healthcare provider.
  • Low blood sugar (hypoglycemia) is a possible side effect of Humalog, Humalog Mix75/25, and Humalog Mix50/50 that may be severe and cause unconsciousness (passing out), seizures, and death. Test your blood sugar levels as your healthcare provider instructs.
  • Humalog, Humalog Mix75/25, and Humalog Mix50/50 start working faster than other insulins that contain regular human insulin and should be taken within fifteen minutes before eating. Humalog can also be taken right after eating a meal.

Important Safety Information for Humalog, Humalog Mix75/25, and Humalog Mix50/50

What is the most important information I should know about Humalog, Humalog Mix75/25, and Humalog Mix50/50?

  • Do not change the insulin you use without talking to your healthcare provider. Doses of oral antidiabetic medicines may also need to change if your insulin is changed.
  • Test your blood sugar levels as your healthcare provider instructs.
  • When used in a pump, do not mix Humalog with any other insulin or liquid. Never use Humalog Mix75/25 or Humalog Mix50/50 in a pump.

Who should not take Humalog, Humalog Mix75/25, or Humalog Mix50/50?

  • Do not take these insulins if your blood sugar is too low (hypoglycemia) or if you are allergic to insulin lispro or any of the ingredients in these insulins.

Before using Humalog, Humalog Mix75/25, or Humalog Mix50/50, what should I tell my healthcare providers?

Tell your healthcare providers:

  • About all of your medical conditions, including liver, kidney, or heart problems.
  • If you are pregnant or breastfeeding.
  • About all the medicines you take, including prescription (especially ones commonly called TZDs [thiazolidinediones]) and nonprescription medicines, vitamins, and herbal supplements.

How should I use Humalog, Humalog Mix75/25, or Humalog Mix50/50?

  • These insulins start working faster than other insulins that contain regular human insulin. You should take Humalog within fifteen minutes before eating or right after eating a meal. You should take Humalog Mix75/25 and Humalog Mix50/50 within fifteen minutes before eating.
  • Always make sure that you receive the correct type of insulin from the pharmacy.
  • Do not use Humalog if it is cloudy, colored, or has solid particles or clumps in it.
  • Do not use Humalog Mix75/25 or Humalog Mix50/50 if they have solid particles or clumps in them. Humalog Mix75/25 and Humalog Mix50/50 should be mixed carefully before each use and should be cloudy or milky after mixing.
  • Do not mix Humalog with insulin other than NPH when using a syringe. Do not mix or dilute Humalog when used in a pump.
  • Never mix Humalog Mix75/25 or Humalog Mix50/50 in the same syringe with other insulin products. Never use Humalog Mix75/25 or Humalog Mix50/50 in a pump.
  • Inject your insulin under your skin (subcutaneously). Never inject into a vein or muscle. Change (rotate) your injection site with each dose. Make sure you inject the correct insulin and dose.
  • Depending on the type of diabetes you have, you may need to take Humalog with a longer-acting insulin or with oral antidiabetic medications.
  • If you forget to take your insulin, your blood sugar may go too high (hyperglycemia), which can lead to serious problems like loss of consciousness (passing out), coma, or even death.
  • Your insulin dose may need to change because of illness, stress, other medicines you take, change in diet, or change in physical activity or exercise.

What are the possible side effects of Humalog, Humalog Mix75/25, or Humalog Mix50/50?

  • Low blood sugar is the most common side effect. There are many causes of low blood sugar, including taking too much insulin. It is important to treat it quickly. You can treat mild to moderate low blood sugar by drinking or eating a quick source of sugar right away. If severe, low blood sugar can cause unconsciousness (passing out), seizures, and death. Symptoms may be different for each person. Be sure to talk to your healthcare provider about low blood sugar symptoms and treatment.
  • Severe life-threatening allergic reactions (whole-body reactions) can happen. Get medical help right away if you develop a rash over your whole body, have trouble breathing, have a fast heartbeat, or are sweating.
  • Reactions at the injection site (local allergic reaction) such as redness, swelling, and itching can happen. If you keep having skin reactions or they are serious, talk to your healthcare provider. Do not inject insulin into a skin area that is red, swollen, or itchy.
  • Skin may thicken or pit at the injection site (lipodystrophy). Do not inject insulin into skin with these types of changes.
  • Other side effects include low potassium in your blood (hypokalemia) and weight gain.
  • Serious side effects can include:
    • -swelling of your hands and feet
    • -heart failure when taking certain pills called thiazolidinediones or "TZDs" with Humalog, Humalog Mix75/25, or Humalog Mix50/50. This may occur in some people even if they have not had heart problems before. Tell your healthcare provider if you have shortness of breath, swelling of your ankles or feet, or sudden weight gain, which may be symptoms of heart failure. Your healthcare provider may need to adjust or stop your treatment with TZDs, Humalog, Humalog Mix75/25, or Humalog Mix50/50.
  • These are not all of the possible side effects. Ask your healthcare providers for more information or for medical advice about side effects.

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch or call 1-800-FDA-1088.

How should I store Humalog, Humalog Mix75/25, and Humalog Mix50/50?

  • Unopened Humalog, Humalog Mix75/25, and Humalog Mix50/50 should be stored in a refrigerator and can be used until the expiration date on the carton or label.
  • Insulin should be stored away from light and heat. Do not use insulin if it has been frozen.
  • Opened vials should be kept at room temperature or in a refrigerator. Opened cartridges or prefilled pens should be kept at room temperature.
  • Once opened, Humalog vials, prefilled pens, and cartridges should be thrown away after 28 days.
  • Once opened, Humalog Mix75/25 and Humalog Mix50/50 vials should be thrown away after 28 days. Opened Humalog Mix75/25 and Humalog Mix50/50 prefilled pens should be thrown away after 10 days.

Humalog, Humalog Mix75/25, and Humalog Mix50/50 are available by prescription only.

For additional information, talk to your healthcare providers and please click to access Full Prescribing Information for Humalog, Humalog Mix75/25, and Humalog Mix50/50, and Patient Prescribing Information for Humalog, Humalog Mix75/25, and Humalog Mix50/50.

Please see Instructions for Use that accompany your pen.

HI BOI CON ISI 29MAR2013