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Welcome to Humalog.com

Understandably, the idea of mealtime insulin can seem overwhelming, but the information, tools, and resources on Humalog.com can help you start to fit Humalog® mealtime insulin into your life. You'll learn what to anticipate during your first day, week, and month and some of the adjustments you'll need to make. Remember, it's all about the small steps!
Indication
Humalog is for use in patients with diabetes to control high blood sugar and should be used with longer-acting insulin, except when used in combination with sulfonylureas in patients with type 2 diabetes.
Humalog, Humalog Mix75/25, and Humalog Mix50/50 are for use in patients with diabetes to control high blood sugar. Humalog should be used with longer-acting insulin, except when used in combination with sulfonylureas in patients with type 2 diabetes.

Humalog (insulin lispro injection [rDNA origin]) is for use in patients with diabetes to control high blood sugar and should be used with longer-acting insulin, except when used in combination with sulfonylureas in patients with type 2 diabetes.

Important Safety Information
Starting or changing insulin therapy should be done cautiously and only under medical supervision.

Humalog should not be used during episodes of low blood sugar (hypoglycemia) or if you are allergic to anything in Humalog.

Humalog is an injectable, fast-acting insulin. Humalog starts working faster than other insulins that contain regular human insulin. Take Humalog within 15 minutes before eating or right after eating a meal. Check your blood sugar levels as told by your healthcare professional.

If you have type 1 diabetes, you need to take a longer-acting insulin in addition to Humalog (except when using an external insulin pump). If you have type 2 diabetes, you may be taking diabetes pills and/or a longer-acting insulin in addition to Humalog.

The safety and effectiveness of Humalog in patients less than 3 years of age have not been established. There are no adequate and well-controlled clinical studies of the use of Humalog in pregnant or nursing women.

Low Blood Sugar
Low blood sugar is the most common adverse effect associated with insulins, including Humalog. Low blood sugar can happen suddenly, and symptoms may be different for each person and may change from time to time. Know your symptoms of low blood sugar. Severe low blood sugar can cause seizures and be life threatening. Follow your healthcare professional's instructions for treating low blood sugar. Talk to your healthcare professional if low blood sugar is a problem for you.

Other Side Effects
Other potential side effects associated with the use of insulins include: low blood potassium, weight gain, changes in fat tissue at the injection site, and allergic reactions. Allergic reactions can happen at the site of injection and over the whole body. Whole-body allergic reactions are less common, but may be life threatening.

Pumps
When used in an external insulin pump, Humalog should not be diluted or mixed with any other insulin. Humalog administration in insulin pumps has not been studied in patients with type 2 diabetes. The infusion set and Humalog should be replaced and a new infusion site selected every 48 hours or less. Glucose monitoring is particularly important for patients using an external insulin pump. Humalog in the external pump should not be exposed to temperatures above 37°C (98.6°F).

Humalog was tested in the MiniMed® Models 506, 507, and 508 insulin pumps using MiniMed® Polyfin® infusion sets.

Humalog was also tested in Disetronic® H-TRONplus® V100 insulin pump (with plastic 3.15 mL insulin reservoir), and the Disetronic D-TRON® and D-TRONplus® insulin pumps (with Humalog 3 mL cartridges) using Disetronic Rapid® infusion sets. A Humalog 3 mL cartridge used in the D-TRON or D-TRONplus should be discarded after 7 days, even if it still contains Humalog. Infusion sets, D-TRON and D-TRONplus cartridge adapters, and Humalog in the external insulin pump reservoir should be discarded every 48 hours or less.

Humalog (insulin lispro injection [rDNA origin]), Humalog Mix75/25 (75% insulin lispro protamine suspension, 25% insulin lispro injection [rDNA origin]), and Humalog Mix50/50 (50% insulin lispro protamine suspension, 50% insulin lispro injection [rDNA origin]) are for use in patients with diabetes to control high blood sugar. Humalog should be used with longer-acting insulin, except when used in combination with sulfonylureas in patients with type 2 diabetes.

Important Safety Information
Starting or changing insulin therapy should be done cautiously and only under medical supervision.

Humalog, Humalog Mix75/25, and Humalog Mix50/50 should not be used during episodes of low blood sugar (hypoglycemia) or if you are allergic to anything in these insulins.

Humalog is an injectable, fast-acting insulin. Humalog Mix75/25 and Humalog Mix50/50 are a mixture of fast-acting and longer-acting insulins. These insulins start working faster than other insulins that contain regular human insulin. Humalog, Humalog Mix75/25, and Humalog Mix50/50 should be taken within 15 minutes before a meal. Humalog can be taken right after eating a meal. Check your blood sugar levels as told by your healthcare professional.

If you have type 1 diabetes, you need to take a longer-acting insulin in addition to Humalog (except when using an external insulin pump). If you have type 2 diabetes, you may be taking diabetes pills and/or a longer-acting insulin in addition to Humalog.

The safety and effectiveness of Humalog in patients less than 3 years of age have not been established. The safety and effectiveness of Humalog Mix75/25 and Humalog Mix50/50 in patients less than 18 years of age have not been established. There are no adequate and well-controlled clinical studies of the use of Humalog, Humalog Mix75/25, or Humalog Mix50/50 in pregnant or nursing women.

Low Blood Sugar
Low blood sugar is the most common adverse effect associated with insulins, including Humalog, Humalog Mix75/25, and Humalog Mix50/50. Low blood sugar can happen suddenly, and symptoms may be different for each person and may change from time to time. Know your symptoms of low blood sugar. Severe low blood sugar can cause seizures and be life threatening. Follow your healthcare professional's instructions for treating low blood sugar. Talk to your healthcare professional if low blood sugar is a problem for you.

Other Side Effects
Other potential side effects associated with the use of insulins include: low blood potassium, weight gain, changes in fat tissue at the injection site, and allergic reactions. Allergic reactions can happen at the site of injection and over the whole body. Whole-body allergic reactions are less common, but may be life threatening.

For other important information, see the Patient Information. Please see full user manual that accompanies the pen.

Humalog® and Humalog® KwikPen™ are registered trademarks of Eli Lilly and Company and are available by prescription only.

For other important information, see the Patient Information.

Humalog® is a registered trademark of Eli Lilly and Company and is available by prescription only.

For other important information, see the Patient Information. Please see full user manual that accompanies each pen.

Humalog®, Humalog® KwikPen™, and HumaPen® LUXURA™ are registered trademarks of Eli Lilly and Company.

Humalog®, Humalog® KwikPen™, and HumaPen® LUXURA™ HD are available by prescription only.

For other important information, see the Humalog, Humalog Mix75/25, and Humalog Mix50/50 Patient Information. Please see full user manual that accompanies each pen.

Humalog® and Humalog® KwikPen™ are registered trademarks of Eli Lilly and Company and are available by prescription only.

Humalog® Mix75/25™, Humalog® Mix50/50™, Humalog® Mix75/25™ KwikPen™, and Humalog® Mix50/50™ KwikPen™ are trademarks of Eli Lilly and Company and are available by prescription only.

For other important information, see the Humalog, Humalog Mix75/25, and Humalog Mix50/50 Patient Information. Please see full user manual that accompanies each pen.

Humalog®, Humalog® KwikPen™, HumaPen® MEMOIR™, and HumaPen® LUXURA™ are registered trademarks of Eli Lilly and Company.

Humalog®, Humalog® KwikPen™, HumaPen® MEMOIR™, and HumaPen® LUXURA™ HD are available by prescription only.

Humalog® Mix75/25™ and Humalog® Mix50/50™ are trademarks of Eli Lilly and Company and are available by prescription only.

For other important information, see the Patient Information. Please see full user manual that accompanies each pen.

Humalog®, Humalog® KwikPen™, HumaPen® MEMOIR™, and HumaPen® LUXURA™ are registered trademarks of Eli Lilly and Company.

Humalog®, Humalog® KwikPen™, HumaPen® MEMOIR™, and HumaPen® LUXURA™ HD are available by prescription only.

For other important information, see the Humalog, Humalog Mix75/25, and Humalog Mix50/50 Patient Information. Please see full user manual that accompanies each pen.

Humalog®, Humalog® KwikPen™, HumaPen® MEMOIR™, and HumaPen® LUXURA™ are registered trademarks of Eli Lilly and Company.

Humalog®, Humalog® KwikPen™, HumaPen® MEMOIR™, and HumaPen® LUXURA™ HD are available by prescription only.

Humalog® Mix75/25™, Humalog® Mix50/50™, Humalog® Mix75/25™ KwikPen™, and Humalog® Mix50/50™ KwikPen™ are trademarks of Eli Lilly and Company and are available by prescription only.

For other important information, see the Patient Information. Please see full user manual that accompanies each pen.

Humalog®, Humalog® KwikPen™, HumaPen® MEMOIR™, and HumaPen® LUXURA™ are registered trademarks of Eli Lilly and Company.

Humalog®, Humalog® KwikPen™, HumaPen® MEMOIR™, and HumaPen® LUXURA™ HD are available by prescription only.

The glucagon design is a trademark of Eli Lilly and Company.

For other important information, see the Humalog, Humalog Mix75/25, and Humalog Mix50/50 Patient Information.

Humalog® is a registered trademark of Eli Lilly and Company and is available by prescription only.

Humalog® Mix75/25™ and Humalog® Mix50/50™ are trademarks of Eli Lilly and Company and are available by prescription only.

For other important information, see the Humalog, Humalog Mix75/25, and Humalog Mix50/50 Patient Information. Please see full user manual that accompanies each pen.

Humalog® is a registered trademark of Eli Lilly and Company and is available by prescription only.

Humalog® Mix75/25™ and Humalog® Mix50/50™ are trademarks of Eli Lilly and Company and are available by prescription only.

The glucagon design is a trademark of Eli Lilly and Company.

For other important information, see the Patient Information.

Humalog® is a registered trademark of Eli Lilly and Company and is available by prescription only.

The glucagon design is a trademark of Eli Lilly and Company.

For other important information, see the Patient Information. Please see full user manual that accompanies the pen.

Humalog® and Humalog® KwikPen™ are registered trademarks of Eli Lilly and Company and are available by prescription only.

Managing Your Diabetes® is a registered trademark of Eli Lilly and Company.

For other important information, see the Patient Information. Please see full user manual that accompanies each pen.

Humalog®, Humalog® KwikPen™, HumaPen® MEMOIR™, and HumaPen® LUXURA™ are registered trademarks of Eli Lilly and Company.

Humalog®, Humalog® KwikPen™, HumaPen® MEMOIR™, and HumaPen® LUXURA™ HD are available by prescription only.

Humalog® Mix75/25™ and Humalog® Mix50/50™ are trademarks of Eli Lilly and Company and are available by prescription only.

For other important information, see the Humalog, Humalog Mix75/25, and Humalog Mix50/50 Patient Information. Please see full user manual that accompanies each pen.

Humalog® is a registered trademark of Eli Lilly and Company and is available by prescription only.

Humalog® Mix75/25™ and Humalog® Mix50/50™ are trademarks of Eli Lilly and Company and are available by prescription only.

For other important information, see the Patient Information. Please see full user manual that accompanies each pen.

Humalog®, Humalog® KwikPen™, HumaPen® MEMOIR™, and HumaPen® LUXURA™ are registered trademarks of Eli Lilly and Company.

Humalog®, Humalog® KwikPen™, HumaPen® MEMOIR™, and HumaPen® LUXURA™ HD are available by prescription only.

Reference
  1. Venekamp WJ, Kerr L, Dowsett SA, et al. Functionality and acceptability of a new electronic insulin injection pen with a memory feature. Curr Med Res Opin. 2006;(22):315-325.

For other important information, see the Humalog, Humalog Mix75/25, and Humalog Mix50/50 Patient Information. Please see full user manual that accompanies each pen.

Humalog®, Humalog® KwikPen™, HumaPen® MEMOIR™, and HumaPen® LUXURA™ are registered trademarks of Eli Lilly and Company.

Humalog®, Humalog® KwikPen™, HumaPen® MEMOIR™, and HumaPen® LUXURA™ HD are available by prescription only.

Humalog® Mix75/25™, Humalog® Mix50/50™, Humalog® Mix75/25™ KwikPen™, and Humalog® Mix50/50™ KwikPen™ are trademarks of Eli Lilly and Company and are available by prescription only.

Reference
  1. Data on file, Lilly USA, LLC (HUM20071024A).

For other important information, see the Humalog, Humalog Mix75/25, and Humalog Mix50/50 Patient Information. Please see full user manual that accompanies each pen.

Humalog®, Humalog® KwikPen™, HumaPen® MEMOIR™, and HumaPen® LUXURA™ are registered trademarks of Eli Lilly and Company.

Humalog®, Humalog® KwikPen™, HumaPen® MEMOIR™, and HumaPen® LUXURA™ HD are available by prescription only.

Humalog® Mix75/25™, Humalog® Mix50/50™, Humalog® Mix75/25™ KwikPen™, and Humalog® Mix50/50™ KwikPen™ are trademarks of Eli Lilly and Company and are available by prescription only.